* Must have over 100 picks by Dec. 31, 2021 to be eligible *
| Athlete | Class | Correct | Incorrect | % | Total |
| Mike Beelby | Staff | 80 | 47 | 63% | 127 |
| Sergio Pineiro | Staff | 75 | 57 | 57% | 132 |
| Sasha Palatnikov | WW | 70 | 51 | 58% | 121 |
| Jimmy Flick | Fly | 68 | 58 | 54% | 126 |
| Joe Gravel | Staff | 68 | 64 | 52% | 132 |
| Mikey Ramos | Staff | 63 | 64 | 50% | 127 |
| Belal Muhammad | WW | 62 | 44 | 58% | 106 |
| Max Griffin | WW | 57 | 47 | 55% | 104 |
| Ryan Bagnal | Staff | 41 | 39 | 51% | 80 |
| Kai Kamaka III | FW | 35 | 25 | 58% | 60 |
| Kyle Nelson | LW | 35 | 22 | 61% | 57 |
| Austin Hubbard | LW | 29 | 14 | 67% | 43 |
| Julio Arce | BW | 29 | 20 | 59% | 49 |
| Ashlee Evans-Smith | BW | 28 | 21 | 57% | 49 |
| Casey O’Neill | Fly | 27 | 20 | 57% | 47 |
| Blaine Moran | Staff | 25 | 19 | 57% | 44 |
| Megan Anderson | FW | 25 | 19 | 57% | 44 |
| Jiri Prochazka | LHW | 24 | 15 | 62% | 39 |
| Jordan Espinosa | Fly | 24 | 18 | 57% | 42 |
| Jamahal Hill | LHW | 20 | 10 | 67% | 30 |
| Billy Quarantillo | FW | 19 | 20 | 49% | 39 |
| Hakeem Dawodu | FW | 18 | 19 | 49% | 37 |
| Stephen Thompson | WW | 18 | 21 | 46% | 39 |
| Khama Worthy | LW | 17 | 7 | 71% | 24 |
| Lando Vannata | LW | 12 | 8 | 60% | 20 |
| Niko Price | WW | 12 | 13 | 48% | 25 |
| Christos Giagos | LW | 11 | 7 | 61% | 18 |
| Jeff Molina | Fly | 11 | 4 | 73% | 15 |
| Michael Trizano | FW | 11 | 8 | 58% | 19 |
| Mike Rodriguez | LHW | 11 | 5 | 69% | 16 |
| Cory Sandhagen | BW | 10 | 5 | 67% | 15 |
| Jordan Williams | WW | 10 | 11 | 48% | 21 |
| Renato Moicano | LW | 9 | 3 | 75% | 12 |
| Vince Morales | BW | 9 | 11 | 45% | 20 |
| Luke Sanders | BW | 8 | 3 | 73% | 11 |
| Randy Costa | BW | 8 | 7 | 53% | 15 |
| Chris Gutierrez | BW | 7 | 3 | 70% | 10 |
| Kai Kara France | Fly | 7 | 3 | 70% | 10 |
| Niklas Stolze | WW | 7 | 8 | 47% | 15 |
| Sam Hughes | SW | 7 | 8 | 47% | 15 |
| Ali AlQaesi | BW | 6 | 2 | 75% | 8 |
| Cody Durden | Fly | 6 | 7 | 46% | 13 |
| Curtis Blaydes | HW | 6 | 10 | 38% | 16 |
| Dan Ige | FW | 6 | 1 | 86% | 7 |
| Jared Gordon | FW | 6 | 1 | 86% | 7 |
| John Dodson | BW | 6 | 10 | 38% | 16 |
| John Makdessi | LW | 6 | 4 | 60% | 10 |
| Justin Gaethje | LW | 6 | 3 | 67% | 9 |
| Nathan Maness | BW | 6 | 15 | 29% | 21 |
| Brad Tavares | MW | 5 | 0 | 100% | 5 |
| Brandon Moreno | Fly | 5 | 3 | 63% | 8 |
| Bryan Barberena | WW | 5 | 10 | 33% | 15 |
| Erin Blanchfield | Fly | 5 | 0 | 100% | 5 |
| Jesse Strader | BW | 5 | 1 | 83% | 6 |
| Kevin Natividad | BW | 5 | 6 | 45% | 11 |
| Ricky Simon | BW | 5 | 6 | 45% | 11 |
| Trevin Giles | MW | 5 | 0 | 100% | 5 |
| Alexa Grasso | Fly | 4 | 1 | 80% | 5 |
| Amir Albazi | Fly | 4 | 1 | 80% | 5 |
| Arnold Allen | FW | 4 | 1 | 80% | 5 |
| Ben Askren | WW | 4 | 1 | 80% | 5 |
| Chris Weidman | MW | 4 | 1 | 80% | 5 |
| Devonte Smith | LW | 4 | 1 | 80% | 5 |
| Diego Ferreira | LW | 4 | 1 | 80% | 5 |
| Harry Hunsucker | HW | 4 | 1 | 80% | 5 |
| Ike Villanueva | LHW | 4 | 3 | 57% | 7 |
| Maurice Greene | HW | 4 | 4 | 50% | 8 |
| Sam Alvey | MW | 4 | 3 | 57% | 7 |
| Tecia Torres | SW | 4 | 2 | 67% | 6 |
| Aaron Phillips | BW | 3 | 3 | 50% | 6 |
| Alessio di Chirico | MW | 3 | 0 | 100% | 3 |
| Carlos Felipe | HW | 3 | 1 | 75% | 4 |
| Casey Kenney | BW | 3 | 3 | 50% | 6 |
| Chase Hooper | FW | 3 | 5 | 38% | 8 |
| Cody Garbrandt | BW | 3 | 1 | 75% | 4 |
| Cortney Casey | Fly | 3 | 5 | 38% | 8 |
| Cynthia Calvillo | Fly | 3 | 0 | 100% | 3 |
| Dakota Bush | LW | 3 | 1 | 75% | 4 |
| Dominick Reyes | LHW | 3 | 0 | 100% | 3 |
| Georges St. Pierre | WW | 3 | 3 | 50% | 6 |
| Gilbert Burns | WW | 3 | 2 | 60% | 5 |
| Henry Cejudo | BW | 3 | 3 | 50% | 6 |
| Ian Heinisch | MW | 3 | 1 | 75% | 4 |
| James Krause | WW | 3 | 2 | 60% | 5 |
| Johnny Walker | LHW | 3 | 2 | 60% | 5 |
| Jordan Leavitt | LW | 3 | 0 | 100% | 3 |
| Journey Newson | BW | 3 | 2 | 60% | 5 |
| Justin Tafa | HW | 3 | 2 | 60% | 5 |
| Kay Hansen | SW | 3 | 0 | 100% | 3 |
| Kevin Holland | MW | 3 | 3 | 50% | 6 |
| Mike Perry | WW | 3 | 3 | 50% | 6 |
| Na Liang | SW | 3 | 2 | 60% | 5 |
| Orion Cosce | WW | 3 | 1 | 75% | 4 |
| Ovince Saint Preux | LHW | 3 | 2 | 60% | 5 |
| Ramiz Brahimaj | WW | 3 | 5 | 38% | 8 |
| Roque Martinez | HW | 3 | 1 | 75% | 4 |
| Sodiq Yusuff | FW | 3 | 0 | 100% | 3 |
| Su Mudaerji | Fly | 3 | 1 | 75% | 4 |
| Tanner Boser | HW | 3 | 2 | 60% | 5 |
| Al Iaquinta | LW | 2 | 3 | 40% | 5 |
| Alexander Hernandez | LW | 2 | 2 | 50% | 4 |
| Aljamain Sterling | BW | 2 | 0 | 100% | 2 |
| Angela Hill | SW | 2 | 3 | 40% | 5 |
| Bill Algeo | FW | 2 | 3 | 40% | 5 |
| Brian Kelleher | BW | 2 | 3 | 40% | 5 |
| Bryce Mitchell | FW | 2 | 3 | 40% | 5 |
| Cameron Else | BW | 2 | 3 | 40% | 5 |
| Charlie Ontiveros | LW | 2 | 3 | 40% | 5 |
| Danny Chavez | FW | 2 | 1 | 67% | 3 |
| Derrick Lewis | HW | 2 | 3 | 40% | 5 |
| Donald Cerrone | LW | 2 | 4 | 33% | 6 |
| Gerald Meerschaert | MW | 2 | 0 | 100% | 2 |
| Jonathan Pearce | FW | 2 | 2 | 50% | 4 |
| Jorge Masvidal | WW | 2 | 1 | 67% | 3 |
| Josh Culibao | FW | 2 | 3 | 40% | 5 |
| Kamaru Usman | WW | 2 | 1 | 67% | 3 |
| Krzyszto Jotko | MW | 2 | 3 | 40% | 5 |
| Kyle Daukaus | MW | 2 | 2 | 50% | 4 |
| Kyler Phillips | BW | 2 | 2 | 50% | 4 |
| Luis Saldana | FW | 2 | 3 | 40% | 5 |
| Montana De La Rosa | Fly | 2 | 1 | 67% | 3 |
| Montserrat Ruiz | SW | 2 | 3 | 40% | 5 |
| Ode Osbourne | Fly | 2 | 3 | 40% | 5 |
| Rafael Alves | FW | 2 | 3 | 40% | 5 |
| Raquel Pennington | BW | 2 | 2 | 50% | 4 |
| Ryan Benoit | Fly | 2 | 1 | 67% | 3 |
| Sean O’Malley | BW | 2 | 1 | 67% | 3 |
| Sijara Eubanks | BW | 2 | 3 | 40% | 5 |
| Terrance McKinney | LW | 2 | 2 | 50% | 4 |
| Terrance McKinney | LW | 2 | 1 | 67% | 3 |
| Tim Elliott | Fly | 2 | 2 | 50% | 4 |
| Tony Gravely | BW | 2 | 0 | 100% | 2 |
| Yancy Medeiros | LW | 2 | 1 | 67% | 3 |
| Adrian Yanez | BW | 1 | 4 | 20% | 5 |
| Aiemann Zahabi | BW | 1 | 2 | 33% | 3 |
| Andrea Lee | Fly | 1 | 2 | 33% | 3 |
| Brianna van Buren | SW | 1 | 3 | 25% | 4 |
| Christian Aguilera | WW | 1 | 5 | 17% | 6 |
| Dustin Jacoby | LHW | 1 | 3 | 25% | 4 |
| Gustavo Lopez | BW | 1 | 1 | 50% | 2 |
| Jan Blachowicz | LHW | 1 | 1 | 50% | 2 |
| Jeremy Stephens | FW | 1 | 4 | 20% | 5 |
| Jordan Griffin | FW | 1 | 4 | 20% | 5 |
| JP Buys | Fly | 1 | 2 | 33% | 3 |
| Juan Espino | HW | 1 | 2 | 33% | 3 |
| Mallory Martin | SW | 1 | 1 | 50% | 2 |
| Maycee Barber | Fly | 1 | 1 | 50% | 2 |
| Miles Johns | BW | 1 | 2 | 33% | 3 |
| Natan Levy | FW | 1 | 2 | 33% | 3 |
| Nate Landwehr | FW | 1 | 1 | 50% | 2 |
| Phil Hawes | MW | 1 | 1 | 50% | 2 |
| Rani Yahya | BW | 1 | 1 | 50% | 2 |
| Rose Namajunas | SW | 1 | 1 | 50% | 2 |
| Steven Peterson | FW | 1 | 3 | 25% | 4 |
| TJ Laramie | FW | 1 | 1 | 50% | 2 |
| Tucker Lutz | FW | 1 | 1 | 50% | 2 |
| Vince Cachero | BW | 1 | 3 | 25% | 4 |
| Cris Cyborg | FW | 0 | 5 | 0% | 5 |
| Johnny Munoz | BW | 0 | 4 | 0% | 4 |
| Julianna Pena | BW | 0 | 3 | 0% | 3 |
| Katlyn Chookagian | Fly | 0 | 3 | 0% | 3 |
| Miesha Tate | BW | 0 | 2 | 0% | 2 |
| Tony Kelley | BW | 0 | 3 | 0% | 3 |